prostaglandin F2 receptor negative regulator; CD9 partner 1; CD9P-1; Glu-Trp-Ile EWI motif-containing protein F; EWI-F; prostaglandin F2-alpha receptor regulatory protein; prostaglandin F2-alpha receptor-associated protein; CD315 (PTGFRN, CD9P1, EWIF, FPRP, KIAA1436)
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Function
- inhibits binding of PGF2-alpha to its specific receptor
- functional coupling with the prostaglandin F2-alpha receptor seems to occur
- interacts with CD9, CD81, CD63, CD82 & CD151
Structure
- contains 6 Ig-like C2-type domains
Compartment
- endoplasmic reticulum membrane
- Golgi, trans-Golgi network membrane
- single-pass type 1 membrane protein (putative)