phosphatidylinositol glycan anchor biosynthesis class U protein; cell division cycle protein 91-like 1; protein CDC91-like 1; GPI transamidase component PIG-U (PIGU, CDC91L1, PSEC0205, UNQ3055/PRO9875)

Function

• component of the GPI transamidase complex
• may be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI
• glycolipid biosynthesis; glycosylphosphatidylinositol- anchor biosynthesis
• forms a complex with PIGK/GPI8, PIGS, PIGT & GPAA1/GAA1

Structure

belongs to the PIGU family

Compartment

• endoplasmic reticulum membrane; multi-pass membrane protein (putative)

Alternative splicing

named isoforms=2

More general terms

• transmembrane 9 protein
• glycoprotein

Additional terms

• glypiated protein

Component of

• GPAA1/PIGK/PIGT/PIGU/PIGS complex

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=128869
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:128869
• OMIM: https://mirror.omim.org/entry/608528
• UniProt: http://www.uniprot.org/uniprot/Q9H490.html