interleukin-28 receptor alpha chain; IL-28R-alpha; IL-28RA; cytokine receptor class-II member 12; cytokine receptor family 2 member 12; CRF2-12; interferon lambda receptor 1; IFN-lambda R1; likely interleukin or cytokine receptor 2 (IL28RA IFNLR1 LICR2)

Function

• IL28RA/IL10RB dimer is a receptor for IL28A, IL28B & IL29
• signal through Jak-STAT pathway (putative)

Structure

• belongs to the type II cytokine receptor family
• contains 1 fibronectin F3 module

Compartment

membrane

Alternative splicing

named isoforms=4

Expression

widely expressed

More general terms

• protein subunit
• membrane protein
• glycoprotein

Component of

• interleukin-28 receptor (IL28 receptor)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1637
• OMIM: https://mirror.omim.org/entry/607404
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=163702
• UniProt: http://www.uniprot.org/uniprot/Q8IU57.html