beta adrenergic receptor
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Introduction
beta-adrenergic receptors mediate catecholamine-induced activation of adenylate cyclase through the action of G proteins
Pharmacology
- beta-adrenergic receptor antagonists (beta blockers) are used in clinically for their pharmacologic effects:
- negative inotropic effects on the heart
- inhibitory effects on conduction through the AV node
- beta-adrenergic receptor agonist are used clinically for indications depending upon their specificity
More general terms
More specific terms
- beta-1 adrenergic receptor; beta-1 adrenoreceptor; beta-1 adrenoceptor (ADRB1, ADRB1R, B1AR)
- beta-2 adrenergic receptor; beta-2 adrenoreceptor; beta-2 adrenoceptor (ADRB2, ADRB2R, B2AR)
- beta-3 adrenergic receptor; beta-3 adrenoreceptor; beta-3 adrenoceptor (ADRB3, ADRB3R, B3AR)
Additional terms
References
- ↑ Molecular Cell Biology (2nd ed) Darnell J; Lodish H & Baltimore D (eds), Scientific American Books, WH Freeman, NY 1990, pg 748