cell division cycle-associated protein 2 (recruits PP1 onto mitotic chromatin at anaphase protein, Repo-Man, CDCA2)

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Function

regulator of chromosome structure during mitosis
required for condensin-depleted chromosomes to retain their compact architecture through anaphase.
acts by mediating recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase & into the following interphase
at anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates
interacts with PPP1CC
phosphorylated by CDK1
may regulate its subcellular location

nucleus
excluded from the nucleolus
present in nucleoplasm throughout the G1, S & G2 stages of the cell cycle
during M phase, it becomes diffuse throughout the cell as the nuclear membrane breaks down, & faintly accumulates later on metaphase chromatin
as the cell progresses to anaphase, it accumulates on chromatin