Zinc fingers & homeoboxes protein 2 (zinc finger & homeodomain protein 2, alpha-fetoprotein regulator 1, AFP regulator 1, regulator of AFP, ZHX2, AFR1, KIAA0854, RAF)

Function

• transcriptional repressor
• forms homodimers
• forms heterodimers with ZHX1 & ZHX3
• heterodimerization with ZHX1 not necessary for repressor activity
• interacts with NFYA

Structure

• belongs to the ZHX family
• contains 2 C2H2-type zinc fingers
• contains 4 homeobox DNA-binding domains

Compartment

nucleus

Expression

ubiquitously expressed

More general terms

• zinc finger protein
• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q9Y6X8.html