zinc fingers & homeoboxes protein 1 (ZHX1)

Function

• transcriptional repressor
• forms heterodimers with ZHX3, prerequisite for repressor activity
• forms homodimers
• forms heterodimers with ZHX2
• interacts with NFYA

Structure

• belongs to the ZHX family.
• contains 2 C2H2-type zinc fingers
  • contains 5 homeobox DNA-binding domains

Compartment

nucleus

Expression

ubiquitously expressed

More general terms

• zinc finger protein

Database

• OMIM: https://mirror.omim.org/entry/604764
• UniProt: http://www.uniprot.org/uniprot/Q9UKY1.html