ECT2 protein (epithelial cell-transforming sequence 2 oncogene, ECT2)
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Function
- binds to RhoA, RhoC & Rac, but does not appear to catalyze guanine nucleotide exchange
- associates with RACGAP1 at anaphase & during cytokinesis
Structure
- contains 2 BRCT domains
- contains 1 DH domain (DBL-homology domain)
- contains 1 PH domain
More general terms
References
- ↑ UniProt http://www.uniprot.org/uniprot/Q9H8V3.html
- ↑ Boguski MS & McCormick F Proteins regulating Ras and its relative. Nature 366:643 1993 PMID: https://www.ncbi.nlm.nih.gov/pubmed/8259209