IFN-inducible ds RNA-dependent protein kinase activator A; PKR-associated protein X; protein activator of the interferon-induced protein kinase; protein kinase, interferon-inducible double stranded RNA-dependent activator (PRKRA, PAC,T RAX, HSD14)

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Function

Structure

  • homodimer
    • self-association may occur via interactions between DRBM domains as follows: DRBM 1/DRBM 1, DRBM 1/DRBM 2, DRBM 2/DRBM 2 or DRBM 3/DRBM3
  • belongs to the PRKRA family
  • contains 3 DRBM (double-stranded RNA-binding) domains

Compartment

cytoplasm, perinuclear region

Alternative splicing

named isoforms=3

Pathology

More general terms

References

Database