TAR RNA-binding protein 2 (trans-activation-responsive RNA-binding protein, TARBP2, TRBP)

Function

• binds double-stranded RNAs with G+C-rich characteristics

Structure

• contains 3 DRBM domains (double-stranded RNA-binding domains)

Compartment

nucleus

Pathology

• binds to HIV-1 TAR RNA located in the long terminal repeat
• acts synergistic with viral TAT protein in HIV-1 expression activation

More general terms

• other protein

Database

• OMIM: https://mirror.omim.org/entry/605053
• UniProt: http://www.uniprot.org/uniprot/Q15633.html