insulin receptor substrate 2; IRS-2 (IRS2)

Function

• may mediate the control of various cellular processes by insulin
• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

• contains 1 IRS-type PTB domain
• contains 1 PH domain

More general terms

• phosphoprotein

Additional terms

• insulin receptor; IR; (INSR)

Database

• UniProt: http://www.uniprot.org/uniprot/Q9Y4H2.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=8660
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8660
• OMIM: https://mirror.omim.org/entry/600797