DNA polymerase epsilon subunit 4 (DNA polymerase epsilon 12 kD subunit, POLE4)

Function

• may play a role in allowing polymerase epsilon to carry out its replication &/or repair function
• interacts with POLE3
• when bound to POLE3, it can associate with POLE1 & POLE2
• phosphorylated upon DNA damage, probably by ATM or ATR

Compartment

nucleus (putative)

More general terms

• protein subunit
• phosphoprotein

Component of

• DNA polymerase epsilon

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5665
• OMIM: https://mirror.omim.org/entry/607269
• UniProt: http://www.uniprot.org/uniprot/Q9NR33.html