DNA polymerase epsilon subunit 3; DNA polymerase epsilon 17 kD subunit; chromatin accessibility complex 17; arsenic-transactivated protein; AsTP; HuCHRAC17; CHRAC-17 (POLE3)

Function

• forms a complex with DNA polymerase epsilon subunit CHRAC1 & binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome-remodeling activity of ISWI/SNF2H & ACF1
• together with CHRAC1, ACF1 & ISWI/SNF2H proteins, it forms the ISWI chromatin-remodeling complex, CHRAC

Compartment

nucleus (putative)

Expression

• expressed in all tissues tested, including, heart, brain, placenta, lung, liver, skeletal muscle, kidney & pancreas

More general terms

• protein subunit

Component of

• DNA polymerase epsilon
• ISWI chromatin remodelling complex CHRAC

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5410
• OMIM: https://mirror.omim.org/entry/607267
• UniProt: http://www.uniprot.org/uniprot/Q9NRF9.html