growth arrest & DNA-damage inducible-45 (GADD45)

Introduction

The 45 presumably reflects apparent molecular weight. Binding of GADD45 to PCNA may displace PCNA from Cdk complexes.

More general terms

• nuclear protein

More specific terms

• growth arrest & DNA-damage-inducible protein GADD45 alpha; GAD45-alpha; DNA-damage-inducible transcript 1; DDIT-1 (GADD45A, DDIT1, GADD45)
• growth arrest & DNA-damage-inducible protein GADD45 beta; myeloid differentiation primary response protein MyD118; negative growth regulatory protein MyD118 (GADD45B, MYD118)
• growth arrest & DNA-damage-inducible protein GADD45 gamma; cytokine-responsive protein CR6; DNA-damage-inducible transcript 2; DDIT-2 (GADD45G CR6 DDIT2)

Additional terms

• growth arrest & DNA-damage-inducible proteins-interacting protein 1 (CR6-interacting factor 1, CRIF1, CK2 beta-associating protein, papillomavirus L2-interacting nuclear protein 1, PLINP-1, GADD45GIP1, PLINP1)