interleukin-1 [IL-1] binding protein

Introduction

A secreted form of IL-1 receptor 2

Function

• acts has decoy
• binds IL-1 reducing IL-1 availability for interaction with IL-1 receptor 1

Expression

enhanced by IL-4 & glucocorticoids

More general terms

• secreted protein

Additional terms

• CDw121b; interleukin-1 receptor type II; IL-1R-2; IL-1R-beta; CD121 antigen-like family member B; CDw121b; CD121b antigen; CD121 (IL1R2, IL1RB)
• interleukin-1 receptor antagonist protein; IL-1ra; IL-1RN; IRAP; IL1 inhibitor; ICIL-1RA (IL1RN, IL1F3, IL1RA)