CDw121b; interleukin-1 receptor type II; IL-1R-2; IL-1R-beta; CD121 antigen-like family member B; CDw121b; CD121b antigen; CD121 (IL1R2, IL1RB)

Function

• receptor for:
  • interleukin-1 alpha (IL-1A)
  • interleukin-1 beta (IL-1B)
  • interleukin-1 receptor antagonist protein (IL-1ra)
• acts has decoy; binds but transduces no signal

Structure

• belongs to the interleukin-1 receptor family
• contains 3 Ig-like C2-type domains (immunoglobulin-like)

Compartment

membrane

Expression

• expression is enhanced by IL-4 & glucocorticoids

More general terms

• interleukin-1 receptor (IL1R)
• glycoprotein
• phosphoprotein
• CD antigen

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7850
• OMIM: https://mirror.omim.org/entry/147811
• UniProt: http://www.uniprot.org/uniprot/P27930.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7850