TRH stimulation test

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Introduction

Prior to the development of ultrasensitive assays for TSH, the TRH stimulation test was the primary method of confiming primary hyperthyroidism.

Indications

Clinical significance

Decreases

conditions that may give a blunted response to TRH include:

Procedure

  • measure baseline TSH
  • TRH 200-500 ug is administered IV
  • TSH is measured at 20, 30 & 60 minutes after TRH administration

More general terms

Additional terms

References

  1. Saunders Manual of Medical Practice, Rakel (ed), WB Saunders, Philadelphia, 1996, pg 339-40