thyrotropin-releasing hormone; thyroliberin; protirelin (TRH)

Function

• induces release of thyroid-stimulating hormone from the anterior pituitary
• induces release of prolactin from the pituitary

Compartment

• secreted from hypothalamus into hypophyseal portal system

Expression

• produced by thyrotropes in the hypothalamus, near the paraventricular nucleus
• produced by gastrointestinal system
• produced by pancreatic islets

Pharmacology

see Relefact

More general terms

• pituitary hormone-releasing hormone; hypothalamic hormone

More specific terms

• Relefact (thyrotropin-releasing hormone, TRH, Thypinone)

Additional terms

• thyroid-stimulating hormone (TSH) or thyrotropin
• thyrotropin-releasing hormone receptor; TRH-R; thyroliberin receptor (TRHR)
• TRH stimulation test

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7200
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7200
• OMIM: https://mirror.omim.org/entry/613879
• UniProt: http://www.uniprot.org/uniprot/P20396.html