replication protein A 70 kD DNA-binding subunit; RP-A p70; replication factor A protein 1; RF-A protein 1; single-stranded DNA-binding protein (RPA1 REPA1 RPA70)
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Function
- subunit of replication factor A
- may be only DNA-binding subunit of replication factor A
- phosphorylated upon DNA damage, probably by ATM or ATR
- interacts with RIP & XPA.
- interacts with RPA4
Structure
belongs to the replication factor A protein 1 family
Compartment
More general terms
Component of
References
- ↑ UniProt http://www.uniprot.org/uniprot/P27694.html
- ↑ NIEHS-SNPs http://egp.gs.washington.edu/data/rpa1/
- ↑ Linn S How many pols does it take to replicate nuclear DNA? Cell 66:185 1991 PMID: https://www.ncbi.nlm.nih.gov/pubmed/1855251
- ↑ de Laat WL et al, Molecular mechonisms of nucleotide excision repair. Genes & Dev 13:768-85, 1999 PMID: https://www.ncbi.nlm.nih.gov/pubmed/10197977