replication protein A 30 kD subunit; RP-A p30; replication factor A protein 4; RF-A protein 4 (RPA4)

Function

• required for simian virus 40 DNA replication in vitro
• role in a very early step in initiation
• subunit of replication factor A

Structure

• heterotrimer of 70, 32/30, & 14 kD chains
• DNA-binding activity may reside exclusively on the 70 kD subunit

Compartment

nucleus

Expression

• preferentially expressed in placental & colon mucosa

More general terms

• protein subunit
• nuclear protein

Component of

• replication factor-A (RFA/RPA)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=29935
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:29935
• UniProt: http://www.uniprot.org/uniprot/Q13156.html