atrial natriuretic factor/peptide/hormone (ANF/ANP/ANH) in plasma

Reference interval

• 20-77 pg/mL

Clinical significance

• high ANP or BNP is associated with increased risk of major cardiovascular event
• high level of either peptide also predicts increased risk for heart failure & atrial fibrillation

Increases

• congestive heart failure
• cardiovascular disease with elevated cardiac filling pressure
• cardiac volume overload
• atrial pacing
• paroxysmal atrial tachycardia

Decreases

• chemical interferences
  • prazosin, urapidil, xipamide

Specimen

• plasma (K2EDTA)
• collect blood into pre-chilled tubes & deliver to the lab on ice
• centrifuge in a refrigerated centrifuge & freeze plasma promptly
• stable for 4 weeks at -25 degrees C

More general terms

• atrial natriuretic factor in blood/plasma

Additional terms

• atrial natriuretic factor/peptide (ANF, ANP)