aurora kinase

Function

• role in phosphorylation of histones, promoting chromosome condensation;
• also interactd with chromosomal passenger proteins including inner centromere proteins & survivin

Pathology

• overexpressed in some human cancers

More general terms

• serine/threonine kinase

More specific terms

• Aurora-related kinase 3; Aurora kinase C; Aurora/IPL1-related kinase 3; ARK-3; serine/threonine protein kinase 13; Aurora/IPL1/Eg2 protein 2; serine/threonine protein kinase aurora-C (AURKC, AIE2, AIK3, ARK3, STK13)
• serine/threonine protein kinase 12; Aurora kinase B; Aurora- & IPL1-like midbody-associated protein 1; AIM-1; Aurora/IPL1-related kinase 2; ARK-2; Aurora-related kinase 2; STK-1; serine/threonine protein kinase aurora-B (AURKB, AIK2, AIM1, ARK2, STK12)
• serine/threonine protein kinase 6; Aurora kinase A; Aurora/IPL1-related kinase 1; ARK-1; Aurora-related kinase 1; hARK1; breast tumor-amplified kinase; serine/threonine protein kinase 15; serine/threonine protein kinase aurora-A (AURKA, AIK, ARK1, AURA...