vesicle transport through interaction with t-SNAREs homolog 1B (vesicle transport v-SNARE protein Vti1-like 1, Vti1-rp1, VTI1B, VTI1, VTI1L, VTI1L1, VTI2)

Function

• v-SNARE
• mediates vesicle transport pathways through interactions with t-SNAREs on target membrane
• specificity of vesicle trafficking
• fusion of the lipid bilayer
• secretion of cytokines associated with cellular senescence
• component of complex with VAMP8 & STX7 in liver
• forms SNARE complex with STX7, STX8 & VAMP8
  • homotypic fusion of late endosomes
• component of SNARE core complex containing STX7, STX8 & VAMP8

Compartment

• intracytoplasmic membrane, cytoplasmic granule

Alternative splicing

named isoforms=2

Expression

ubiquitous

More general terms

• SNARE protein

Database

• OMIM: https://mirror.omim.org/entry/603207
• UniProt: http://www.uniprot.org/uniprot/Q9UEU0.html