interleukin enhancer-binding factor 2; nuclear factor of activated T-cells 45 kD (ILF2, NF45, PRO3063)

Function

• heterodimeric complex with ILF3
• complex may regulate transcription of the IL2 gene during T-cell activation
• formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA
• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

contains 1 DZF domain

Compartment

nucleus, nucleolus

More general terms

• interleukin enhancer binding factor
• phosphoprotein

Additional terms

• interleukin enhancer binding factor 3

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3608
• OMIM: https://mirror.omim.org/entry/603181
• UniProt: http://www.uniprot.org/uniprot/Q12905.html