nuclear receptor-binding factor 2; NRBF-2; comodulator of PPAR & RXR (NRBF2, COPR)

Function

• modulation of transcriptional activation by nuclear receptors (putative)
• transcriptional activator (in vitro)
• interacts with PPARA, PPARD & PPARG
• interacts with RARA, RARG & RXRA in the presence of bound ligand
• interacts with SCOC

Compartment

nucleus, cytoplasm

Alternative splicing

named isoforms=2

Expression

• expressed in keratinocytes, liver, placenta

More general terms

• transcriptional adaptor protein; transcriptional coactivator
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=29982
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:29982
• UniProt: http://www.uniprot.org/uniprot/Q96F24.html