integrin alpha-4/beta-7
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Function
- role in adhesive interactions of leukocytes
- receptor for fibronectin, VCAM1 & MADCAM1
- recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin
- recognizes the sequence L-D-T in MADCAM1
Structure
- subunits: integrin alpha-V, integrin beta-7
Compartment
membrane