integrin alpha-8/beta-1

^[1]

Function

functions in the genesis of kidney & probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures
recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGFB1, TGFB3 & VTN
NPNT is probably its functional ligand in kidney genesis
neuronal receptor for TNC; mediates cell-cell interactions & regulates neurite outgrowth of sensory & motor neurons

membrane