integrin alpha-8 (ITGA8)

Function

• associates with integrin beta-1 (integrin alpha-8/beta-1)

Structure

• composed of an heavy & a light chain linked by a disulfide bond
• belongs to the integrin alpha chain family
• contains 7 FG-GAP repeats

Compartment

membrane

Expression

• expressed in mesenchymal cells, including alveolar myofibroblasts, kidney mesangial cells & hepatic stellar cells & vascular & visceral smooth muscle (at protein level)

More general terms

• integrin-alpha

Component of

• integrin alpha-8/beta-1

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8516
• OMIM: https://mirror.omim.org/entry/604063
• UniProt: http://www.uniprot.org/uniprot/P53708.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=8516