glycoprotein IIB/IIIA

Introduction

Mediates platelet aggregation through binding of fibrinogen. Weak intercellular bridges are established via multiple platelets binding the same fibrinogen molecule.

More general terms

• integrin

Additional terms

• abciximab (ReoPro)
• Eptifibatide (Integrilin)
• fibrinogen; coagulation factor-1
• fibronectin; FN; cold-insoluble globulin; CIG; contains: anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3 (FN1, FN)
• platelet
• Tirofiban (Aggrastat)
• vitronectin; S-protein; serum-spreading factor; V75; contains: vitronectin V65 subunit; vitronectin V10 subunit; somatomedin-B (VTN)
• von Willebrand factor; vWF; ristocetin cofactor; factor VIII related antigen; contains: von Willebrand antigen 2 (VWF, F8VWF)