C-C motif chemokine 7; monocyte chemoattractant protein 3; monocyte chemotactic protein 3; MCP-3; NC28; small-inducible cytokine A7 (CCL7, MCP3, SCYA6, SCYA7)

Function

• chemotactic factor
• chemotactic for monocytes & eosinophils
• not chemotactic for neutrophils
• augments monocyte anti-tumor activity
• induces the release of gelatinase B
• can bind heparin
• binds to CCR1, CCR2 & CCR3

Structure

• O-glycosylated
• monomer
• belongs to the intercrine beta (chemokine CC) family

Compartment

secreted

More general terms

• CC chemokine; beta chemokine

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6354
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6354
• OMIM: https://mirror.omim.org/entry/158106
• UniProt: http://www.uniprot.org/uniprot/P80098.html