coatomer subunit alpha; alpha-coat protein; alpha-COP; HEP-COP; HEPCOP; contains: xenin; xenopsin-related peptide; contains: proxenin (COPA)

Function

• coatomer alpha subunit
• probably interacts with PEX11A
• precursor of xenin

Structure

contains 6 WD repeats

Compartment

• cytoplasm (putative)
• Golgi membrane
• peripheral membrane protein; cytoplasmic side
• cytoplasmic vesicle, COPI-coated vesicle membrane
• the coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it (putative)

Alternative splicing

named isoforms=2

Expression

• uniformly expressed in a wide range of adult & fetal tissues
• Xenin is found in gastric, duodenal & jejunal mucosa
• circulates in the blood

More general terms

• coatomer protein/subunit (COP)
• WD repeat protein family
• phosphoprotein

More specific terms

• xenin

Database

• UniProt: http://www.uniprot.org/uniprot/P53621.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1314
• OMIM: https://mirror.omim.org/entry/601924