aggrecan core protein; cartilage-specific proteoglycan core protein; CSPCP; chondroitin sulfate proteoglycan core protein 1; contains: aggrecan core protein 2 (ACAN, AGC1, CSPG1, MSK16)

From Aaushi
Jump to navigation Jump to search

Function

Structure

Compartment

Alternative splicing

named isoforms=3 Additional isoforms seem to exist

Expression

Pathology

More general terms

References

  1. Ruoslahti E, Yamaguchi Y. Proteoglycans as modulators of growth factor activities. Cell. 1991 Mar 8;64(5):867-9. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/2001586
  2. 2.0 2.1 UniProt http://www.uniprot.org/uniprot/P16112.html
  3. 3.0 3.1 Journal Watch 25(10):81, 2005 Glasson SS, Askew R, Sheppard B, Carito B, Blanchet T, Ma HL, Flannery CR, Peluso D, Kanki K, Yang Z, Majumdar MK, Morris EA. Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis. Nature. 2005 Mar 31;434(7033):644-8. PMID: https://www.ncbi.nlm.nih.gov/pubmed/15800624
    Stanton H, Rogerson FM, East CJ, Golub SB, Lawlor KE, Meeker CT, Little CB, Last K, Farmer PJ, Campbell IK, Fourie AM, Fosang AJ. ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro. Nature. 2005 Mar 31;434(7033):648-52. PMID: https://www.ncbi.nlm.nih.gov/pubmed/15800625
  4. Functional glycomics gateway - glycan binding Note: Aggrecan http://www.functionalglycomics.org/glycomics/GBPServlet?&operationtype=view&cbpId=cbp_hum_Ctlect_351

Database