large proline-rich protein BAT3; HLA-B-associated transcript 3; protein G3 (BAT3, BAG6, G3)

Function

• role in ricin-induced apoptosis
• cleavage by CASP3 releases a C-terminal peptide that plays a role in ricin-induced apoptosis
• interacts with ricin A chain

Structure

• contains 1 ubiquitin-like domain

Compartment

• nucleus
• the C-terminal fragment generated by caspase-3 is cytoplasmic

Alternative splicing

named isoforms=3

More general terms

• proline-rich protein
• nuclear protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7917
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7917
• OMIM: https://mirror.omim.org/entry/142590
• UniProt: http://www.uniprot.org/uniprot/P46379.html