lamin-B

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Function

lamins are components of the nuclear lamina (see lamin)
lamin A & lamin C filaments cross-link into an orthogonal lattice (nuclear lamina), which is attached via lamin B to the inner nuclear membrane through interactions with a lamin B receptor
increased phosphorylation of the lamins occurs before nuclear envelope disintegration & probably plays a role in regulating lamin associations

↑ Holtz D et al The CaaX motif of lamin A functions in conjunction with the nuclear localization signal to target assembly to the nuclear envelope. Cell 59:969 1989 PMID: https://www.ncbi.nlm.nih.gov/pubmed/2557160
↑ Seabra MC, Reiss Y, Casey PJ, Brown MS, Goldstein JL. Protein farnesyltransferase and geranylgeranyltransferase share a common alpha subunit. Cell. 1991 May 3;65(3):429-34. PMID: https://www.ncbi.nlm.nih.gov/pubmed/2018975111