DNA repair protein RAD52 homolog (RAD52)

Function

• role in DNA double-stranded break repair
• role in genetic recombination & DNA repair by promoting the annealing of complementary single-stranded DNA & by stimulation of the RAD51 recombinase
• phosphorylated upon DNA damage, probably by ATM or ATR
• forms a undecameric ring

Structure

belongs to the RAD52 family

Compartment

nucleus (putative)

More general terms

• DNA-binding protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5893
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5893
• OMIM: https://mirror.omim.org/entry/600392
• UniProt: http://www.uniprot.org/uniprot/P43351.html