p21-activated kinase 6 (PAK6)
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Function
- activated kinase acts on a variety of targets
- interacts tightly with GTP-bound but not GDP-bound CDC42/p21 & RAC1 (putative)
- interacts with the androgen receptor
- autophosphorylated when activated by CDC42/p2
Structure
- belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily
- contains 1 CRIB domain
- contains 1 protein kinase domain