COUP transcription factor 1; COUP-TF1; COUP transcription factor I; COUP-TF I; nuclear receptor subfamily 2 group F member 1; V-erbA-related protein 3; EAR-3 (NR2F1, EAR3, ERBAL3, TFCOUP1)

Function

• coup (chicken ovalbumin upstream promoter) transcription factor binds to the ovalbumin promoter &, in conjunction with another protein (S300-II) stimulates initiation of transcription
• binds to both direct repeats & palindromes of the 5'-AGGTCA-3' motif
• interacts with COPS2

Structure

• belongs to the nuclear hormone receptor family, NR2 subfamily
• contains 1 nuclear receptor DNA-binding domain

Compartment

nucleus (putative)

More general terms

• nuclear hormone receptor NR2 subfamily
• zinc finger protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7025
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7025
• OMIM: https://mirror.omim.org/entry/132890
• UniProt: http://www.uniprot.org/uniprot/P10589.html