insulinase, insulysin, insulin protease or insulin-degrading enzyme
Jump to navigation
Jump to search
Function
- pepetidase/ protease
- substrates include:
Compartment
- cytosol
- peroxisomes
- extracellular fluid
- plasma membrane
- internal membranes.
Expression
More general terms
References
- ↑ Selkoe DJ. Clearing the brain's amyloid cobwebs. Neuron. 2001 Oct 25;32(2):177-80. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/11683988
- ↑ 2.0 2.1 Vekrellis K, Ye Z, Qiu WQ, Walsh D, Hartley D, Chesneau V, Rosner MR, Selkoe DJ. Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme. J Neurosci. 2000 Mar 1;20(5):1657-65. PMID: https://www.ncbi.nlm.nih.gov/pubmed/10684867 {from Selkoe's group}