zinc finger protein 295; zinc finger & BTB domain-containing protein 21 (ZNF295, KIAA1227, ZBTB21)

Function

• acts as a transcription repressor
• phosphorylated upon DNA damage, probably by ATM or ATR
• homodimer, interacts with ZFP161

Structure

• contains 1 BTB/POZ domain
• contains 8 C2H2-type Zn+2 fingers

Compartment

nucleus

Alternative splicing

named isoforms=2

Expression

ubiquitous in fetal & adult tissues

More general terms

• C2H2 type zinc finger protein
• nuclear protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=49854
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:49854
• UniProt: http://www.uniprot.org/uniprot/Q9ULJ3.html