activator of apoptosis harakiri; neuronal death protein DP5; BH3-interacting domain-containing protein 3 (HRK, BID3)

Function

• activates apoptosis & interacts selectively with survival-promoting proteins Bcl-2 & Bcl-X(L)

Structure

• one of the 'BH3 only' domain members of the bcl-2 family of proteins
• the BH3 motif is required for the induction of cell death

More general terms

• BH3 subfamily protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=8739
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8739
• OMIM: https://mirror.omim.org/entry/603447
• UniProt: http://www.uniprot.org/uniprot/O00198.html