MSS1 protein; 26S proteasome subunit 7 (PSMC2, MSS1)

Function

• regulatory ATPase of the 26S proteasome
• confers ATP dependency & substrate specificity to the 26S proteasome
• interacts with NDC80 & SQSTM1
• interacts with HIV-1 Tat, positive modulator of Tat-mediated transactivation

Structure

belongs to the AAA ATPase family

Compartment

cytoplasm, nucleus

More general terms

• adenosine triphosphatase (ATPase)

Component of

• 26S proteasome

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5701
• OMIM: https://mirror.omim.org/entry/154365
• UniProt: http://www.uniprot.org/uniprot/P35998.html