myosin 16 (MYO16, KIAA0865, MYO16B)

Function

• actin-based motor molecules with ATPase activity
• role in targeting catalytic subunit of protein phosphatase 1 during brain development
• binds PPP1CA &/or PPP1CC
• binds F-actin (ATP-sensitive)

Structure

• contains 7 ANK repeats
• contains 1 IQ domain
• contains 2 myosin head-like domains

Compartment

• cytoplasm
• found in puncta in soma & processes of astrocytes & dissociated cerebellar cells with morphology of migrating granule cells

Alternative splicing

named isoforms=4

More general terms

• unconventional myosin

Database

• UniProt: http://www.uniprot.org/uniprot/Q9Y6X6.html