bacteremia

^[1]^[2]^[3]^[4]^[5]

Introduction

The presence of viable bacteria in the circulating blood. (see sepsis)

PCV13 vaccines have reduced incidence of bacteremia in young children & shifted the most-commonly isolated pathogens from pneumococcus to E coli, S aureus, & Salmonella^[4]

absence of fever, elevated serum C-reactive protein & criteria for systemic inflammatory response syndrome with negative predictive value of 0.99^[3]
a normal blood WBC count does not rule out bacteremia^[2]
shaking chills is a positive predictor of bacteremia
normal food consumption is a negative predictor^[5]

↑ Stedman's Medical Dictionary 26th ed, Williams & Wilkins, Baltimore, 1995
↑ ^2.0 ^2.1 Seigel TA et al. Inadequacy of temperature and white blood cell count in predicting bacteremia in patients with suspected infection. J Emerg Med 2012 Mar; 42:254. PMID: https://www.ncbi.nlm.nih.gov/pubmed/20674238
↑ ^3.0 ^3.1 Anderson RE and Walls RM Is My Patient Bacteremic? NEJM Journal Watch. Aug 6, 2014 Massachusetts Medical Society (subscription needed) http://www.jwatch.org
Lindvig KP et al. How do bacteraemic patients present to the emergency department and what is the diagnostic validity of the clinical parameters; temperature, C-reactive protein and systemic inflammatory response syndrome? Scand J Trauma Resusc Emerg Med. 2014 Jul 15; PMID: https://www.ncbi.nlm.nih.gov/pubmed/25027551
↑ ^4.0 ^4.1 Greenhow TL, Hung YY, Herz A. Bacteremia in children 3 to 36 months old after introduction of conjugated pneumococcal vaccines. Pediatrics 2017 Apr; 139:e20162098. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/28283611 <Internet> http://pediatrics.aappublications.org/content/early/2017/03/08/peds.2016-2098
↑ ^5.0 ^5.1 Komatsu T, Takahashi E, Mishima K et al. A simple algorithm for predicting bacteremia using food consumption and shaking chills: A prospective observational study. J Hosp Med 2017 Jul; 12:510. PMID: https://www.ncbi.nlm.nih.gov/pubmed/28699938