gamma-glutamyltransferase (GGT) or gamma-glutamyltranspeptidase

Function

• plasma membrane enzyme may be involved in amino acid transport (see gamma-glutamyl cycle)

Compartment

• present in plasma membrane & microsomal fractions

Expression

• hepatic tissue levels increase in response to microsomal enzyme induction

Pathology

• elevated serum levels observed in patients with hepatobiliary disease

Laboratory

• gamma-glutamyltransferase in body fluid
  • gamma-glutamyltransferase in amniotic fluid
  • gamma-glutamyltransferase in dialysis fluid
  • gamma-glutamyltransferase in semen
  • gamma-glutamyltransferase in serum
  • gamma-glutamyltransferase in urine

More general terms

• glutamyltransferase
• plasma membrane protein
• multisubunit protein

More specific terms

• gamma-glutamyltransferase 6 (gamma-glutamyltranspeptidase 6, GGT 6, [contains: gamma-glutamyltransferase 6 heavy chain; gamma-glutamyltransferase 6 light chain], GGT6)
• gamma-glutamyltransferase 7; GGT 7;gamma-glutamyltransferase-like 3; gamma-glutamyltransferase-like 5; gamma-glutamyltranspeptidase 7; contains: gamma-glutamyltransferase 7 heavy chain; gamma-glutamyltransferase 7 light chain (GGT7, GGTL3, GGTL5)
• gamma-glutamyltransferase light chain 3 (GGTLC3)
• gamma-glutamyltransferase-1 (GGT1, gamma-glutamyltranspeptidase-1, CD224 antigen)
• gamma-glutamyltransferase-2 (GGT2, gamma-glutamyltranspeptidase-2)
• gamma-glutamyltransferase-5 (GGTLA1, GGT5)

Additional terms

• gamma glutamyl cycle
• gamma-glutamyltransferase (GGT) in serum
• gamma-glutamyltransferase-like protein