gamma-glutamyltransferase 6 (gamma-glutamyltranspeptidase 6, GGT 6, [contains: gamma-glutamyltransferase 6 heavy chain; gamma-glutamyltransferase 6 light chain], GGT6)

Function

• cleaves glutathione conjugates (putative)
• active site is located in the light chain (putative)
• glutathione metabolism

(5-L-glutamyl)-peptide + an amino acid <--> peptide + 5-L-glutamyl amino acid

Structure

• heterodimer composed of the light & heavy chains
• belongs to the gamma-glutamyltransferase family

Compartment

membrane

Alternative splicing

named isoforms=2

More general terms

• gamma-glutamyltransferase (GGT) or gamma-glutamyltranspeptidase
• glycoprotein
• membrane protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1249
• UniProt: http://www.uniprot.org/uniprot/Q6P531.html