pulseless electrical activity; electromechanical dissociation (PEA)
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Classification
ECG electrical activity other than VF/VT
- electromechanical dissociation
- idioventricular rhythms
- ventricular escape rhythms
- bradyasystolic rhythm
- postdefibrillation idioventricular rhythms
Etiology
- hypovolemia
- hypoxemia
- cardiac tamponade
- tension pneumothorax
- hypothermia
- massive pulmonary embolus
- drug overdose
- hyperkalemia
- severe acidosis
- massive acute myocardial infarction
Diagnostic procedures
Management
- assess for presence of pulse, begin CPR if no pulse
- recheck for pulse after 2 minutes of CPR
- cardiac monitor to assess rhythm
- use Doppler to assess blood flow
- if blood flow, treat for severe hypotension
- if no blood flow continue CPR
- establish IV access
- intubate (IV access takes precedence over intubation)
- consider possible causes & treat
- epinephrine 1 mg IV push every 3-5 min
- administration of 1st dose within 1 to 3 minutes[3]
- longer time to epinephrine administration is associated with diminished survival in children with in-hospital cardiac arrest & pulseless electrical activity[4]
- atropine no longer recommended[2]
- adenosine may be used[2]
- if no response
- high dose epinephrine *
- NaHCO3 if appropriate #
* high dose epinephrine: 2-5 mg IV push every 3-5 min; 1 mg, 3 mg, 5 mg 3 minutes apart; 0.1 mg/kg every 3-5 min
# NaHCO3 not indicated early in resuscitation, acidosis is generally secondary to inadequate ventilation, dose is 1 meq/kg IV followed by 0.5 meq/kg every 10 min
More general terms
References
- ↑ Manual of Medical Therapeutics, 28th ed, Ewald & McKenzie (eds), Little, Brown & Co, Boston, 1995, pg 180
- ↑ 2.0 2.1 2.2 2010 American Heart Association Guidelines for CPR and Emergency Cardiovascular Care Oct. 18, 2010 Comparison Chart of Key Changes http://www.heart.org/idc/groups/heart-public/@wcm/@ecc/documents/downloadable/ucm_317267.pdf
- ↑ 3.0 3.1 Young K cites BMJ article For Cardiac Arrest with Nonshockable Rhythm, Quicker Epinephrine Is Better. Physician's First Watch, May 22, 2014 David G. Fairchild, MD, MPH, Editor-in-Chief Massachusetts Medical Society http://www.jwatch.org
- ↑ 4.0 4.1 Andersen LW et al Time to Epinephrine and Survival After Pediatric In-Hospital Cardiac Arrest. JAMA. 2015;314(8):802-810. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/26305650 <Internet> http://jama.jamanetwork.com/article.aspx?articleid=2429714
Tasker RC, Randolph AG Pediatric Pulseless Arrest With "Nonshockable" Rhythm. Does Faster Time to Epinephrine Improve Outcome? PMID: https://www.ncbi.nlm.nih.gov/pubmed/26305646 JAMA. 2015;314(8):776-777 - ↑ 5.0 5.1 Gaspari R et al. Emergency department point-of-care ultrasound in out-of- hospital and in-ED cardiac arrest. Resuscitation 2016 Sep 27 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/27693280 <Internet> http://www.resuscitationjournal.com/article/S0300-9572(16)30478-6/abstract