lead nephropathy

Etiology

• pica
• alcoholic beverages stored in lead crystal
• lead batteries
• aerosolized lead

Pathology

• accumulation of lead in proximal renal tubules
• chronic tubulointerstitial nephritis

Clinical manifestations

• Fanconi's syndrome
• renal insufficiency
• hypertension
• saturnine gout

Laboratory

• aminoaciduria
• potassium excretory defects
• glycosuria
• serum lead concentrations are generally normal
• excessive urine excretion of chelated lead after injection of EDTA (diagnostic)

More general terms

• nephropathy
• interstitial nephritis

More specific terms

• saturnine gout

Additional terms

• lead poisoning (plumbism)
• lead [Pb]