mixed acid-base disorder

Etiology

• cardiac arrest
  • respiratory acidosis
  • metabolic acidosis
• sepsis
  • metabolic acidosis, lactic acidosis
  • respiratory alkalosis
• drug intoxication
  • metabolic acidosis (all)
  • metabolic alkalosis (vomiting)
  • respiratory alkalosis (salicylates)
  • respiratory acidosis (sedatives)
• renal failure
  • metabolic acidosis
  • metabolic alkalosis
    • oral alkali
    • antacids
    • cationic exchange resins
• respiratory failure
• hepatic failure
  • respiratory alkalosis
  • metabolic alkalosis
    • vomiting
    • diuretics
  • metabolic acidosis due to inability to metabolize lactate

Laboratory

• arterial blood gas
  • pH may be low, high or normal
• plasma lactate if lactic acidosis is suspected

Management

• specific for specific etiology
• bicarbonate for pH of < 7.10

More general terms

• acid-base disorder

Additional terms

• acid-base balance
• cardiac arrest
• renal failure; kidney failure
• sepsis
• toxicity; poisoning; overdose