pigmented lesions of the oral mucosa
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Etiology
- oral melanocytic macule
- any area of mouth
- discrete or diffuse, brown to black macules
- remains indefinitely
- diffuse melanin pigmentation
- any area of mouth
- may be physiologic or due to smoking
- remains indefinitely
- melanocytic nevus
- any area of mouth
- discrete, localized, brown to black
- remains indefinitely
- malignant melanoma
- any area of mouth
- variable morphology, brown to black, may be painless
- expands & invades early; metastasis leads to death
- Addison's disease
- generally on buccal mucosa
- blotches of blueish-black to dark brown pigmentation; diffuse pigmentation of skin
- lesions response to steroid therapy
- Peutz-Jeghers syndrome
- any area of mouth
- dark brown spots on lips & buccal mucosa; pigment around lips, nose, eyes, & on hands
- pigmented lesions remain indefinitely
- drug ingestion
- tranquilizers, oral contraceptives, antimalarials
- any area of mouth
- brown, black or gray areas of pigmentation
- lesions disappear with cessation of drug
- amalgam tattoo
- gingiva & mucobuccal fold
- small blue-black pigmented areas associated with embedded amalgam; may appear as radiopaque particles
- remains indefinitely
- heavy metal pigmentation
- black hairy tongue
- dorsum of tongue
- elongation of filiform papillae of tongue; brown to black
- long duration; may disappear spontaneously
- Fordyce's disease (spot)
- buccal & labial mucosa
- aggregation of numerous small yellow spots just beneath the buccal mucosa; no symptoms
- remains indefinitely
More general terms
More specific terms
- Addison's disease (primary adrenal failure)
- Fordyce spot (granule)
- melanocytic nevus (mole)
- melanoma
- Peutz-Jeghers syndrome (hamartomatous intestinal polyposis)
References
- ↑ Harrison's Principles of Internal Medicine, 13th ed. Isselbacher et al (eds), McGraw-Hill Inc. NY, 1994, pg 203