vasoactive intestinal polypeptide-secreting tumor (VIPoma)
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Pathology
- tumor of pancreatic islet D1 cells
- 60% malignant
Clinical manifestations
Laboratory
- serum potassium: hypokalemia
- serum chloride: hypochlorhydria
- serum vasoactive intestinal polypeptide (VIP) > 75 pg/mL
- see ARUP consult[3]
More general terms
Additional terms
- islet cell tumor; pancreatic neuroendocrine neoplasm; nesidioblastoma
- vasoactive intestinal polypeptide (VIP); [precursor contains: intestinal peptide PHV-42; intestinal peptide PHM-27; peptide histidine methioninamide 27; vasoactive intestinal peptide]
References
- ↑ Harrison's Principles of Internal Medicine, 14th ed. Fauci et al (eds), McGraw-Hill Inc. NY, 1998, pg 585
- ↑ Medical Knowledge Self Assessment Program (MKSAP) 15, 17. American College of Physicians, Philadelphia 2009, 2015
- ↑ 3.0 3.1 ARUP Consult: Vasoactive Intestinal Polypeptide Secreting Tumor - VIPoma The Physician's Guide to Laboratory Test Selection & Interpretation https://arupconsult.com/content/vasoactive-intestinal-polypeptide-secreting-tumor